Neomed Labs Pacific Biomarkers PAIRimmune are now Nexelis
 
Biomarkers × clear filter

search & filter

Our assay menus are offered in both alphabetical and category-based formats.

search by:

or filter by:

Bone Formation

OC (Osteocalcin) - ECL

Analyte: Osteocalcin
Specimen Type: Serum, EDTA Plasma, Inquire for additional option(s)
Biological or Clinical Significance: Osteocalcin, a 49 amino acid peptide is the major noncollagen protein of bone. It contains three gamma-carboxyglutamic acid (GLA) residues at positions 17, 21 and 24 and is, therefore, also known as bone gla-protein or BGP. The exact biological function of osteocalcin is not known but the three gamma-carboxyglutamic acid residues confer on it a…

OPG (Osteoprotegerin)

Analyte: Osteoprotegerin
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance: Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues; it has a molecular weight of 60 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. OPG inhibits the change of RANK…

OPN (Osteopontin), Plasma

Analyte: Osteopontin
Specimen Type: EDTA Plasma
Biological or Clinical Significance: Osteopontin (OPN), also known as early T lymphocyte activation 1 (Eta-1), is a secreted multifunctional glycoprotein.  Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression.  Based on gene structure and chromosomal location, OPN is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also…

OPN (Osteopontin), Urine

Analyte: Osteopontin
Specimen Type: Urine
Biological or Clinical Significance: Osteopontin (OPN), also known as early T lymphocyte activation 1 (Eta-1), is a secreted multifunctional glycoprotein.  Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression.  Based on gene structure and chromosomal location, OPN is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also…

PINP (N-Terminal Propeptide of Type I Collagen) - RIA

Analyte: Aminoterminal Propeptide of Type I Collagen
Specimen Type: Serum
Biological or Clinical Significance: Collagen type I is present in soft connective tissues and bone, where it constitutes more than 90% of the organic matrix.  During bone formation, collagen type I is synthesized from pro-collagen type I, which is secreted from fibroblasts and osteoblasts.  Type I procollagen contains N- and C-terminal extensions which are removed by specific proteases during…
back to top