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Cardiovascular

CXCL-12 SDF-1 (Stromal Cell Derived Factor-1)

Analyte: Stromal Cell Derived Factor-1
Specimen Type: PlatletPoor EDTA Plasma
Biological or Clinical Significance: SDF-1 alpha or stromal derived factor 1 alpha (also known as  CXCL12) has weak sequence homology with other CXC chemokines and with members of the CC (β) chemokines sub-family In contrast to other chemokines genes, which are on chromosomes 4 or 17, the SDF-1 gene is on chromosome 10. SDF-1 also has a higher degree…

Galectin-3

Analyte: Galectin-3
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance: Galectin-3 is a structurally unique member of a family of beta-galactosidase-binding lectins.  Expression of galectin-3 has been associated with the epithelium and inflammatory cells including macrophages, neutrophils and mast cells.  Galectin-3 has been implicated in a variety of biological processes important in heart failure, including myofibroblast proliferation, fibrogenensis, tissue repair, cardiac remodeling and inflammation.

MCP-1 (Monocyte Chemotactic Protein-1) - chemi

Analyte: Monocyte Chemotactic Protein-1
Specimen Type: Serum
Biological or Clinical Significance: Monocyte Chemotactic Protein-1 (MCP-1), also known as CCL2, MCAF and TDCF, is encoded by the human JE gene. It belongs to the CC chemokine family. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. Elevated levels of MCP-1 have also been found in connection with inflammation, Alzheimer’s…

NT-ProBNP (N-Terminal Pro B-Type Natriuretic Peptide)*

Analyte: N-terminal ProB-type Natriuretic Peptide
Specimen Type: Serum, Heparin Plasma, EDTA Plasma
Biological or Clinical Significance: The clinical utility of CNH assays for B-type natriuretic peptide (BNP) and the N-terminal part of the propeptide of BNP (NT-proBNP) has been confirmed for screening of heart disease, stratification of patients with congestive heart failure, detection of left ventricular systolic and/or diastolic dysfunction, and differential diagnosis of dyspnea.

SDF-1 (Stromal Cell Derived Factor-1) (CXCL-12)

Analyte: Stromal Cell Derived Factor-1
Specimen Type: Platelet Poor EDTA Plasma; please contact nexelis for collection information
Biological or Clinical Significance: SDF-1 alpha or stromal derived factor 1 alpha (also known as  CXCL12) has weak sequence homology with other CXC chemokines and with members of the CC (β) chemokines sub-family In contrast to other chemokines genes, which are on chromosomes 4 or 17, the SDF-1 gene is on chromosome 10. SDF-1 also has a higher degree…
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