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Endocrine Function

EPO (Erythropoietin)

Analyte: Erythropoietin
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance: Erythropoietin (Epo) is a glycoprotein hormone consisting of 165 amino acids with four complex carbohydrate chains attached to the peptide at four linkage sites. It has a molecular weight of 36 kilodaltons, 40% attributed to the carbohydrate chains. Epo is the primary regulator of erythropoiesis, stimulating the proliferation and differentiation of erythroid precursor cells in…

HGH (Human Growth Hormone)

Analyte: Human Growth Hormone
Specimen Type: Serum, Inquire for additional option(s)
Biological or Clinical Significance: GH testing is not recommended for general screening. It is primarily ordered on those with symptoms of growth hormone abnormalities, as a follow-up to other abnormal hormone test results, or to help evaluate pituitary function. Growth hormone tests are used to help identify excess or diminished GH production. They are part of the diagnostic work-up…

TGF ß-1 (Transforming Growth Factor ß-1) - Chemi.

Analyte: Transforming Growth Factor ß-1
Specimen Type: Serum
Biological or Clinical Significance: Transforming Growth Factor Beta 1(TGF-Beta1), is encoded by the human TGF-Beta gene. It a polypeptide member of the transtroming growth factor beta superfamily and cytokines. TGF-beta molecules are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta signaling begins with binding to a TGF-beta RII and…

TGF ß-1 (Transforming Growth Factor ß-1) - ELISA

Analyte: Transforming Growth Factor ß-1
Specimen Type: Platlet Poor EDTA Plasma; Please contact nexelis for collection instructions
Biological or Clinical Significance: Transforming growth factor (TGF), a ‘factor’ that promoted the transformation of cultured fibroblasts into a tumor-like phenotype, was subsequently found to be more of a tumor suppressor than tumor promoter and to be a mixture of two proteins, TGF-α and TGF-β. These molecules are members of a superfamily that includes TGF-β 1 through 5, bone…

TGF ß-1 (Transforming Growth Factor ß-1), Urine

Analyte: Transforming Growth Factor ß-1
Specimen Type: For information on this assay, please contact nexelis.
Biological or Clinical Significance: NULL
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