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CTGF (Connective Tissue Growth Factor)

Analyte: Connective Tissue Growth Factor
Specimen Type: Serum
Biological or Clinical Significance: CTGF, a member of the CCN protein family, is relevant in many physiological and pathological processes.  Both clinical and experimental studies have demonstrated that CTGF is overexpressed in fibrotic human liver and in experimental animal models of liver fibrogenesis.  CTGF is detectable in various human fluids (serum, plasma, and urine) and can potentially provide information…

Surfactant Protein A

Analyte: Surfactant Protein A
Specimen Type: Heparin Plasma, Inquire for additional option(s)
Biological or Clinical Significance: Surfactant Protein A (SP-A; surfactant-associated protein A – SFTPA; pulmonary surfactant-associated protein A – PSPA) is the major protein component of the lung surfactant in mammals.  It belongs, together with SP-D (surfactant protein D), to the collectin family of proteins, whose members contain collagen-like and C-type lectin domains.  The protein has a structure of six…

Tenascin C

Analyte: Tenascin C
Specimen Type: EDTA Plasma
Biological or Clinical Significance: Tenascin-C is an extracellular matrix glycoprotein that is composed of 210-400 kDa subunits consisting of four domains.  One subunit has a TA domain at the N-terminal end, then an epidermal growth factor-like sequence domain (EGF-like domain), a fibronectin type III (FN III) repeat domain, and a fibrinogen-like domain at the C-terminal end.  There is an…

TGF ß-1 (Transforming Growth Factor ß-1) - Chemi.

Analyte: Transforming Growth Factor ß-1
Specimen Type: Serum
Biological or Clinical Significance: Transforming Growth Factor Beta 1(TGF-Beta1), is encoded by the human TGF-Beta gene. It a polypeptide member of the transtroming growth factor beta superfamily and cytokines. TGF-beta molecules are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta signaling begins with binding to a TGF-beta RII and…

TGF ß-1 (Transforming Growth Factor ß-1), Urine

Analyte: Transforming Growth Factor ß-1
Specimen Type: For information on this assay, please contact nexelis.
Biological or Clinical Significance: NULL
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