Neomed Labs Pacific Biomarkers PAIRimmune are now Nexelis

search & filter

Our assay menus are offered in both alphabetical and category-based formats.

search by:

or filter by:

PIIINP (N-Terminal Propeptide of Type III Collagen)

Analyte: Procollagen Type III N-Propeptide
Specimen Type: Serum, Heparin Plasma, Inquire for additional options(s)
Optimum Volume: 1.0 mL
2-8°C -20°C -70°C
5 days 2 years 2 years
Reporting units: ng/mL
Method: RIA
Biological or Clinical Significance:

Type III (PIIINP) collagen is derived from a larger protein, type III procollagen. Increased concentrations of PIIINP are found in a number of conditions where accumulation and/or degradation of connective tissue takes place, e.g. in fibroproliferative, haematological, endocrinological and malignant diseases. Thus changes in PIIINP levels are not specific for a particular disease but reflect the involvement and altered metabolism of type III collagen. In growth deficient children, the induction of growth is reflected in increasing serum PIIINP. Liver fibrosis and cirrhosis of various aetiologies increase serum concentration of PIIINP. Serum PIIINP is increased in myeloproliferative diseases, particularly during the active phases of myelofibrosis. The serum concentration of PIIINP also appears to reflect the repair process and scar formation after a myocardial infarction.

Principle of Test Method:

The PIIINP RIA kit is based on the competitive radioimmunoassay technique.

Download this assay page in pdf format.

PIIINP (N-Terminal Propeptide of Type III Collagen)
back to top
contact us now

contact us

  • This field is for validation purposes and should be left unchanged.