Preclinical Assay Development and In Vivo Services

Custom In Vivo Models and Testing Solutions

Selecting the appropriate in vivo model for your assays is critical for the success of your preclinical research program. At Nexelis, we designed and developed disease specific in vivo models alongside bespoke personalized model development services. Our wealth of experience and capabilities allows us to help answer our clients’ research questions and aid with the most appropriate study design. We provide non-regulated, preclinical development solutions that include performing experiments, analysis, reporting, and technical writing.

In addition, our preclinical service capabilities include custom designed and BSL-2 challenge in vivo models. Our scientists specialize in immunology, bacteriology, virology, physiology, and cell-based assays analysis. These platforms are utilized within our diverse portfolio of projects, including a range of assays to assess both humoral and cellular immunity.

In Vivo Model Research

Studies performed within Canadian Council on Animal Care (CCAC) and the American Association for Accreditation of Laboratory Animal Care (AAALAC) facility:

Pathogens

Influenza, Respiratory Syncytial Virus (RSV), Herpes Simplex Virus (HSV), Epstein-Barr Virus (EBV), Measles, Vesicular Stomatitis Virus-Vaccinia (VSV-vaccina)

Immunogenicity, reactogenicity, efficacy

  • Discovery to preclinical
  • Efficacy: BSL-2 challenge models with pathogens, tumor growth, immune disorders, Lymphocytic Choriomeningitis Virus (LCMV)
  • Reactogenicity: systemic and local

Chronic disorder models

Mysethenia Gravis, arthritis

BSL-3 SARS-CoV-2 model

(Coming Soon)

Polyclonal antibody generation

Learn more about our In Vivo services and expertise.