Mesoscale Discovery (MSD)
For biomarker, immunogenicity, PK, and cell-based assays, MSD provides higher sensitivity than conventional colorimetric methods. It also enables multiplexing and is compatible with complex matrices.
This robust form of immunoassay enables precise detection of up to 100 analytes simultaneously. This allows quantification of numerous different biomarkers in one sample, revealing information about biological and disease processes. It is especially useful for bioanalysis, such as PK, biomarker, and immunogenicity studies.
An enzyme-linked immune absorbent spot (ELISpot) assay quantitatively measures cellular functions in immune cells. It can be used to assess adaptive and innate immune responses, e.g., to vaccines, via measurement of antigen-specific T-cells. This highly adaptable method is very sensitive to a wide range of responses.