Protein Sciences Services

Molecular Biology and Protein Expression, Purification, and Characterization

When you partner with the Nexelis, a Q² Solutions Company, we will work closely with you from concept through delivery. Our services are fully flexible according to your needs and can be engaged as stand-alone tests or as a comprehensive package. You receive proteins tailored to your specifications in scale, purity, activity, and other analytical characteristics — on a timeline that meets your needs.

We welcome complex projects including the de novo design, construction, purification, and analytical characterization of novel proteins. From pseudoparticles to monoclonal antibodies, the Nexelis protein sciences group has experience in the purification of a wide range of proteins including large, complex molecules produced by a variety of expression platforms. In addition, we have access to a wide variety of analytical methods using state-of-the-art instrumentation. We work in close collaboration with the clinical testing group for subsequent efficacy testing.

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Our Experience

At Nexelis, you have access to a team of flexible and reputable scientists who will apply their innovative thinking, scientific discipline, and agility to solve your protein science challenges using a flexible approach. We specialize in molecular biology, protein expression, protein purification, and characterization, and offer laboratory and consultation services adapted to your needs.

With expertise in supporting biotech and large pharmaceutical companies, our team implements personalized strategies that ensure quality and consistency of delivered material that is optimally suited to each client’s needs.

Take advantage of our experience with a wide range of prokaryotic and eukaryotic recombinant proteins, such as:

  • Viral, bacterial, and human proteins; monoclonal antibodies (mAbs)
  • Hetero-oligomers and specific conformers
  • Lipoproteins and integral membrane proteins
  • Particle-forming proteins (i.e., virus-like protein (VLPs), pseudovirus)
  • Generation of stable cell lines
Customized Characterization Monitoring of selected key parameters Sponsor’s Needs Immunoassay requirements and success criteria Construct Design Sequence optimization Expression Strategy Various systems Stable clone selection Purification Process feasibility assessment Product Delivery Antigen delivery to immunological assay development groups